Q: Loud lifters. No power 2008 Ford Fusion

Hello - the lifter noise and loss of power are, I believe 2 separate issues. The noisy lifter problem is somewhat common on this engine - sometimes caused by poor oil supply (oil sludging). The loss of power issue is often caused by throttle body issues, or dirty injectors. You don’t mention a "Check Engine" light, but I would certainly check for problem codes, whether the CEL is illuminated or not. I would recommend an inspection of the engine for both conditions by a mobile, professional mechanic, such as one from YourMechanic, who will come to your location, diagnose this problem, give you an accurate assessment of damage and cost estimate for repairs.