Noise above 40 mph
Try to rotate the tires to see if the noise changes on your 2004 Ford E-350 Econoline. I have had many noises caused by uneven tire wear (https://www.yourmechanic.com/services/uneven-tire-wear-inspection), alignment issues (https://www.yourmechanic.com/article/how-to-know-if-you-need-a-wheel-alignment-by-robert-tomashek), or lack of tire rotations (https://www.yourmechanic.com/article/how-often-do-i-need-to-rotate-my-tires). You already replaced...